Litts Drug Eruption & Reaction Database - Presented by CRC Press

The most comprehensive database on adverse drug reactions for our profession.David Adams MD


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BreastfeedingGeriatricPediatric

  • TRADE NAME: Nuplazid (Acadia)
  • INDICATIONS: Hallucinations and delusions associated with Parkinson’s disease psychosis
  • CLASS: Antipsychotic, Antipsychotic, atypical
  • HALF-LIFE: 57 hours
  • FDA APPROVAL DATE: 04/29/2016
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    Amiodarone, Carbamazepine, Chlorpromazine, Clarithromycin, Disopyramide, Drugs known to prolong the QT interval, Gatifloxacin, Indinavir, Itraconazole, Ketoconazole, Moxifloxacin, Phenytoin, Procainamide, Quinidine, Rifampin, Sotalol, St John's Wort, Strong CYP3A4 inhibitors and inducers, Thioridazine, Ziprasidone
  • PREGNANCY: No available data to inform drug-associated risk
  • See adverse reactions attributed to class:

    Antipsychotic

    Antipsychotic, atypical

INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS

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Page last updated 08/22/2024

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Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric

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